Scientific Program

Registration and Coffee

Welcome and introduction

Malena Cohen-Cymberknoh, MD; CF Center, Hadassah Medical Center, Jerusalem

Venous thromboembolism and anticoagulation considerations in CF

Tal Lavi, Pharm D; CF Center, Carmel Medical Center, Haifa

Physiotherapy management in CF patients with upper limb deep vein thrombosis

Tomer Israeli, Physiotherapist; CF Center, Hadassah Medical Center, Jerusalem

The use of VEST for treatment in patients with CF

Gil Sokol, Physiotherapist; CF Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan

Personalized exercise prescription in CF patients

Ronen Bar-Yoseph, MD; CF Center, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa

Physiotherapy during the coronavirus pandemic

Hadas Mantin, Physiotherapist; Graub CF Center, Schneider Children's Medical Center, Petah Tikva, Eynav Manor, CF Center, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa

Strengthening muscles with songs: a new tool in pediatric physical therapy

Maayan Klein, Physical therapist; Children's writer

Coffee Break

Session B: "Epidemiology and Physiology data"

Chairs: Michal Shteinberg, MD PhD and Moshe Ashkenazi, MD

 (Session conducted in English, except*)

Extended protocol for bowel preparation in CF adults undergoing screening colonoscopy*

Hila Alterovich, RD, MAN; CF Center, Carmel Medical Center, Haifa

Israel CF Patient Registry data from 2019

Meir Mei Zahav, MD; Graub CF Center, Schneider Children's Medical Center, Petah Tikva

National prenatal carrier screening influence on CF birth rate and disease phenotype

Miri Dotan, MD; Graub CF Center, Schneider Children's Medical Center, Petah Tikva

The association between lung inhomogeneity, CFTR function and structural lung disease

Oded Breuer, MD; CF Center, Hadassah Medical Center, Jerusalem

Data from the Adult CF Clinic in Beilinson Medical Center

Moshe Heshing, MD; Schneider Children's Medical Center and Beilinson CF Center, Petah Tikva

Time for lung transplant in CF? Seek under the "spirometry lamp"

Daphna Vilozni, Phd; CF Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan

Lunch- CF Professional Group Meetings:

• Physicians
• Nurses and Research Coordinators
• Dieticians
• Physiotherapists 
• Psychologists and Social workers

Session C: "Airway infections in CF- What else can we do?"

Chairs: Karin Yaacobi-Bianu, MD and Ronen Bar-Yoseph, MD

(Session conducted in English)

Challenges in the eradication of Pseudomonas

Malena Cohen-Cymberknoh, MD; CF Center, Hadassah Medical Center, Jerusalem

Is there a benefit for inhaled antibiotics in people with CF not infected with Pseudomonas? An ECFSPR data analysis

Michal Shteinberg, MD PhD; Pulmonary Institute and CF Center, Carmel Medical Center, Haifa

Achromobacter infection in patients with CF: Data from the ECFS Patient Registry

Eitan Kerem, MD; CF Center, Hadassah Medical Center, Jerusalem

COVID in European CF patients

Meir Mei Zaav, MD; Graub CF Center, Schneider Children's Medical Center, Petah Tikva

Nebulized bacteriophage therapy for chronic Pseudomonas aeruginosa pulmonary infections in CF patients

Xilla Ussery, MD; BiomX

Coffee Break and Exhibition

Session D: "CF in the new era: Are we close to the end of the tunnel?"

Chairs: Joel Reiter, MD and Hagit Levin, MD

(Session conducted in English)

The latest scientific developments in treatment of CFTR mutations

Mark Higgins, MBBS; Vertex Pharmaceuticals Inc., Boston, USA

Pregnancy & Trikafta – Case presentation

Lior Tzivian, MD; Graub CF Center, Schneider Children's Medical Center, Petah Tikva

Multiple Pregnancies in Cystic Fibrosis: Maternal and Fetal Outcomes and Impact on Disease Course

Maya Dabby, Medical Student; The Hebrew University of Jerusalem

Pregnancy and Parenthood in CF-The MAYFLOWERS and HOPeCF studies

Jennifer L. Taylor-Cousar, MD, MSCS, ATSF; Divisions of Pulmonary Sciences and Critical Care Medicine and Pediatric Pulmonology; Co-Director and CF TDC Director, Adult CF Center, National Jewish Health, USA

Development of ELX- 02 for CF patients with Nonsense Mutations 

Ali Hariri MD, Senior Vice President, Chief Medical Officer, Eloxx Pharmaceuticals

Do we need more drugs after Trikafta?

John Sheridan, PhD ; Director of Research, the CF Foundation, Bethesda, Maryland

Breakfast

Session E: "New and personalized therapies in CF"

Chairs: Dario Prais, MD and Michal Gur, MD

(Session conducted in English)

Challenges with future drug development in the era of widespread, highly effective modulator therapy

Jane Davis, MD; National Heart & Lung Institute, Imperial College London

Royal Brompton & Harefield NHS Foundation Trust, NIHR Senior Investigator, London, UK

2D intestinal organoids for personalized medicine in CF and a comparison to donor-matched nasal cell cultures

Liron Birimberg Schwartz, MD; CF Center, Hadassah Medical Center, Jerusalem

Antisense oligonucleotide splicing modulation- a novel CF therapeutic approach for W1282X mutation

Batsheva Kerem, PhD; Life Sciences Institute, Hebrew University, Jerusalem and Splisense

Trikafta treatment in CF patients 6-12 years of age

Dario Prais, MD; Graub CF Center, Schneider Children's Medical Center, Petah Tikva

Triple combination CFTR modulation therapy- the Israeli experience

Adi Dagan, MD; CF Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan

Coffee Break and Exhibition

Session F: "Pearls in CF- General issues”

Chairs: Micha Aviram, MD and Adi Dagan, MD

(Session conducted in English)

Is Primary Sclerosing Cholangitis (PSC) a CF-related disorder? -Electrophysiological testing and full sequencing

Michael Wilschanki, MD; CF Center, Hadassah Medical Center, Jerusalem

The association between serum IgG levels and disease severity parameters

Michal Gur, MD; CF Center, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa

Sleep disturbances in CF and PCD over time, before and after modulator Therapy

Maya Lehavi, Medical Student; The Hebrew University of Jerusalem

The changing face of CF: the challenge of a new perspective on life

Eddie Landau, MPhil, PhD;  Graub CF Center, Schneider Children's Medical Center, Petah Tikva

Telemedicine in CF

Ifat Sarouk, MD; CF Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical

Closing remarks

Malena Cohen-Cymberknoh, MD; CF Center, Hadassah Medical Center, Jerusalem

Lunch