07:30-09:30  Parallel Session- Nurses

      Coral Hall

      Sponsored by    

07:30-08:30- Extrahepatic HCV manifestations

                      פרופ' אלי צוקרמן

08:30-08:45 - ליווי מטופל co-infection ושיתוף הפעולה עם יחידת הHIV

                      רימה קרמסקי  א. אחראית יחידת כבד מרכז רפואי רמב"ם

08:45-09:00 מקום האחות בהדרכה בטיפול בחולי כבד שומני ובשילוב עם HCV

                    יעל חריף  א. אחראית יחידת כבד מרכז רפואי בלינסון

09:00-09:15- ביופסיית כבד – כאב חווית המטופל ומה שביניהם

                     קרן צארף  א. אחראית יחידת כבד מרכז רפואי שיבא

09:15-09:30 איתור חולי הפטיטיס C  במחוז חיפה וגליל מערבי

                    אורלי אזולאי , א. אחראית יחידת כבד מרכז רפואי כרמל


08:00-09:30 Session 4

"Blue" Hall

Chairs: Prof. Rifaat Safadi, Dr. Ella Veitzman


08:00-08:08 NK cell apoptosis correlates with fibrosis progression in Nonalcoholic-Fatty Liver-Disease via insulin receptor and mTOR pathway

Johnny Amer , Ahmad Salhab , Sarit Doron , Rifaat Safadi Liver & Gastroenterology Units,, Hadassah-Hebrew University Hospital., Israel 

08:08-08:16  Circulating Levels of the Chemokine CCL24 and its Receptor in Patients with Non-alcoholic Fatty Liver Disease

Yaakov Maor 1 , Dan Haberman 2 , Michal Segal-Salto 3 , Avi Katav 3 , Sharon Hashmueli 3 , Jacob George 2 , Adi Mor 3 1 Institute of Gastroenterology and Hepatology, Kaplan Medical Center, Israel 2 Heart Center, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew university, Jerusalem, Israel 3 NA, ChemomAb ltd, Israel 

08:16-08:24  CM-101, a novel CCL24 blocking monoclonal antibody ameliorates hepatic injury in NASH induced mouse model

Ziv Ben-Ari 1 , Michal Segal-Salto 2 , Avi Katav 2 , Sharon Hashmueli 2 , Jacob George 3 , Dan Haberman 3 , Yaacov Maor 4 , Adi Mor 2 1 Liver Diseases Center, Sheba Medical Center, Israel 2 Chemomab, ChemomAb Ltd, Israel 3 Heart Institute, Kaplan Medical Center, Israel 4 Liver Diseases service, Kaplan Medical Center, Israel 

 

08:24-08:32  Non-alcoholic Fatty Liver Disease in Non-obese Young Adults

Yaakov Maor 1 , Salah Daher 2,3 , Eran Israeli 3 , Stephen DH Malnick 4 , Ehud Melzer 1 , Lior Katz 5 1 Institute of Gastroenterology and Hepatology, Kaplan Medical Center, Israel 2 NA, the Israeli Defense Force, Israel 3 Department of Gastroenterology and Hepatology, Hadassah Medical Center, Israel 4 Department of Internal Medicine C, Kaplan Medical Center, Israel 5 Department of Gastroenterology, Sheba Medical Center, Tel-Hashomer, Israel 

 

08:32-08:40  The association of dietary meat type and its cooking method with non-alcoholic fatty liver disease and insulin resistance

Dana Ivancovsky 1 , Revital Kariv 2,3 , Naomi Fliss-Isakov 2,3 , Muriel Webb 2,3 , Oren Shibolet 2,3 , Shira Zelber-Sagi 1,2 1 University of Haifa, School of Public Health, Israel 2 Tel Aviv Medical Center, Department of Gastroenterology, Israel 3 Tel Aviv University, Faculty of Medicine, Israel 

 

08:40-08:48  The impact of bariatric surgery on nonalcoholic fatty liver disease and cardiovascular risk utilizing non-invasive measures

Carmit Netanel 1 , David Goitein 2 , Moshe Rubin 2,3 , Michael Shechter 3,4 , Yeruham Kleinbaum 5 , Sima Katsherginsky 5 , Hila Hermon 2 , Rina Hemi 6 , Keren Tsaraf 1 , Ardita Donuzi 1 , Michal Safran 1 , Irina Tachlytski 1 , Amir Herman 3,7 , Pablo Ortiz 8 , Ziv Ben-Ari 1,3 1 Liver Disease Center, Sheba Medical Center, Tel Hashomer, Israel 2 Bariatric and Metabolic Surgery, Sheba Medical Center, Tel Hashomer, Israel 3 Sackler School of Medicine, Tel Aviv University, Israel 4 Leviev Heart center, Sheba Medical Center, Tel Hashomer, Israel 5 Deparmtent of Radiology, Sheba Medical Center, Tel Hashomer, Israel 6 Institute of Endocrinology, Sheba Medical Center, Tel Hashomer, Israel 7 Department of Orthopedics, Sheba Medical Center, Tel Hashomer, Israel 8 OWL, Parque Tecnológico de Bizkaia, Spain 

 

08:48-08:56  Predictors of minimal hepatic encephalopathy in asymptomatic HCV patients before and after antiviral treatment. Preliminary results from the EMERALD study.

Sharon Levy , Nir Bar , Oren Shibolet , Helena Katchman Liver unit,Department of Gastroenterology and Liver Diseases, Tel-Aviv Sourasky medical center and the Sackler faculty of medicine, Israel 

 

09:00-09:20  Hot topic 2: Withdrawal NUCs in HBeAg-negative patients

Dr. Ashley Brown

Consultant Hepatologist, Imperial College Healthcare NHS Trust

St. Mary’s Hospital, UK

 

09:20-09:28  Hepatitis delta seroprevalence and molecular characterization of hepatitis B and delta confection in Israel

Rachel Shirazi 1 , Daniela Ram 1 , Aviya Rakovsky 1 , Efrat Bucris 1 , Yael Gozlab 1 , Pninit Shaked-Mishan 2 , Orit Picard 3 , Yonat Shemer-Avni 5 , Haim Ben-Zvi 6 , Ora Halutz 8 , Ella Mendelson 1 , Rifaat Safadi 9 , Yoav Lurie 7, Ziv Ben-Ari 4 , Orna Mor 1 1 Central Virology Laboratory, Ministry of Health, Israel 2 Microbiology Laboratory, Carmel Medical Center, Israel 3 Gastroenterology Laboratory, Sheba Medical Center, Israel 4 Liver Disease Center, Sheba Medical Center, Israel 5 Microbiology Laboratory, Soroka Medical Center, Israel 6 Microbiology Laboratory, Rabin Medical Center, Israel 7 Liver Unit, Shaare Zedek Medical Center, Israel 8 Microbiology Laboratory, Sourasky Medical Center, Israel 9 Liver Unit, Hadassah Medical Center, Israel 


09:30-09:55 Coffee Break, Visit to the poster exhibit & Exhibit Hall


10:05-11:31 Session 5

"Blue" Hall

Chairs: Dr. Yaakov Maor, Dr. Yoram Menachem


10:05-10:13  Occurrence and Recurrence of Malignancies Post DAA Treatment in 5.1% of Patients- Single Center Experience

Assaf Issachar , Orly Sneh-Arbib , Marius Braun , Amir Shlomai , evelin Oxtrud , Chen Karuani , Hagar Banai , Yael Harif , Ran Tur-Kaspa , Michal Cohen-Naftali Liver institute, Rabin Medical Center-beilinson hospital, Israel 

 

10:15-10:35  Hot topic 3- Occurrence and recurrence of HCC with DAAs treatment for HCV

Prof. Steven Flamm

Division of Hepatology ,Northwestern University Feinberg School of Medicine ,Chicago, Illinois, USA

 

10:35-10:43  Cutting the Israeli Hepatitis C related "Hepatocellular Carcinoma" in 2016

Izhar Levy 1 , Vered ben-Hakoon 2 , Rawi Hazzan 3 , Tova Nesher 1 , Igbaria Saleh 3 , Alexander Shtarkman 3 , Ravit Geva 5 , Tarek Saadi 2 , Ella Veitsman 2 , Oren Shibolet 4 , Rifaat Safadi 1 , Yoram Menachem 4 1 Liver unit, Hadassah Hospital, Israel 2 Liver unit, Rambam Hospital, Israel 3 Liver unit, HaEmek Hospital, Israel 4 Liver unit, Ichilov Hospital, Israel 5 Oncology, Ichilov Hospital, Israel 

 

10:43-10:51  Hepatitis C virus infection is associated with increased rate of malignancy other than B-cell lymphoma and HCC

Eli Zuckerman 1 , Hedy S. Rennert 2 , Gad Rennert 2 1 Liver Unit, Carmel Medical Center, Israel 2 Department of Community Medicine and Epidemiology, Carmel Medical Center, Technion Faculty of Medicine, Israel 

 

10:51-10:59  High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures

Meital Gal-Tanamy 1 , Shira Perez 1,2 , Anat Lavi-Itzkovitz 1,3 , Antony Kaspi 4 , Ateret Davidovich 1 , Ana Tobar 5 , Alejandro Livoff 6 , Assy Nimer 7 , Evgeny Solomonov 8 , Assam El-Osta 4 , Gur Yaari 3 , Salomon M Stemmer 9 , Izhak Haviv 2 1 Molecular Virology Lab, Faculty of Medicine in the Galilee, Bar-Ilan University, Israel 2 Cancer Personalized Medicine and Diagnostic Genomics Lab, Faculty of Medicine in the Galilee, Bar-Ilan University, Israel 3 Bioengineering, Faculty of Engineering, Bar-Ilan University, Israel 4 Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Monash University, Australia 5 Institute of Pathology, Rabin Medical Center, Beilinson Campus, Israel 6 Department of Pathology, Barzilay Medical Center, Israel 7 Internal Medicine Department A, Western Galilee Medical Center, Israel 8 Department of Surgery, Ziv Medical Center, Israel 9 Davidoff Center, Rabin Medical Center, Beilinson Campus, Israel 

 

10:59-11:07  Fecal microbiota profiles as diagnostic biomarkers in cirrhosis and hepatocellular carcinoma and the impact of life style and nutrition

Lena Lapidot 1,2,3 , Rita Nosenko 4 , Bella Gayshis 2 , Maria Likhter 2 , Wadia Hazou 2 , Dana Ben-Ami 2 , Tatiana Bradichevsky 2 , Ofir Harnoy 2 , Tal Engel 2 , Itai Kalisky 2 , Peretz Weiss 2 , Ella Veitsman 2 , Oranit Cohen-Ezra2 , Yana Davidov 2 , Omry Koren 4 , Michal Safran 1,2 , Ziv Ben-Ari 2,3 1 Liver research laboratory, Chaim Sheba Medical Center, Tel-Hashomer, Israel 2 Liver Diseases Center, Chaim Sheba Medical Center, Tel-Hashomer, Israel 3 The Sackler School of Medicine, Tel-Aviv University, Israel 4 Faculty of Medicine, Bar-Ilan University, Israel 

 

11:07-11:15  The potential of curcumin in combination with direct acting antivirals to treat Hepatitis C virus infection and prevent viral induced oncogenesis

Oshri Yosefov Levi 1 , Ateret Davidovich 1 , Shimon Steingart 2 , Yoav Lurie 2 , Meital Gal Tanamy 1 1 molecular virology, Bar Ilan University faculty of medicine in the galilee, Israel 2 Digestive Disease Institute, Sha'are Zedek Medical Center, Israel 

 

11:15-11:23  Role of Lens culinaris Agglutinin-Reactive Fraction of α-Fetoprotein (AFP-L3) and Des-Gamma-Carboxy Prothrombin ((DCP), Alone or in Combination, as Biomarkers for Hepatocellular Carcinoma surveillance

Ziv Ben-Ari 1,3 , Gal Ben-Haim 1 , Ella Weitzman 1 , Oranit Cohen-Ezra 1,3 , Peretz Wiess 1 , Tania Berdichevsky 1 , Itai Kalisky 1 , Dana Silverberg 1 , Shani Dor-Hai 1 , Avishag Hassid 1 , Keren Tzaref 1 , Orly Azoulay 2 , Eyal Ashkenazi 2 , Yulia Kovalev 2 , Eli Zuckerman 2,4 1 Liver Diseases Center, Sheba medical Center, Israel 2 Liver Unit, Carmel Medical Center, Israel 3 Sackler School of Medicine, Tel Aviv University, Israel 4 Rappaport Faculty of Medicine, Technion, Israel 

 

11:23-11:31  Distinct antibody-mediated immune response against HCV correlates with spontaneous viral clearance

Anastasia Brodov 1 , Yoav Bahat 1 , Ateret Davidovich 1 , Sivan Eliyahu 1 , Shiri Elmedvi 1 , Yael Weiss 2 , Jonathan Gershoni 2 , Marius Braun 3 , Assy Nimer 4 , Meital Gal-Tanamy 1 1 Molecular Virology Lab, Faculty of Medicine in the Galilee, Bar-Ilan University, Israel 2 Virology and Immunology Lab, Faculty of Biology, Tel Aviv University, Israel 3 Liver Institute, Rabin Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel 4 Liver Institute, Western Galilee Hospital, Nahariya, Israel 


11:35-11:50 Coffee Break, Visit to the poster Exhibit & Exhibit Hall


11:50-13:00 Session 6

"Blue" Hall

Chairs: Dr. Ohad Ezion, Dr. Matthias Carlebach


11:50-12:10  Hot Topic 4- Reactivation of HBV during treatment for HCV with DAAs

Prof. Daniel Shouval, Liver Unit, Hadassah- Hebrew University Hospital, Ein- Kerem

 

  12:10-12:18 

The Real-World Israeli experience of treating chronic hepatitis C , genotype 1 and 4 patients with advanced fibrosis with grazoprevir plus elbasvir: a large multi-center cohort.

Eli Zuckerman 1 , Eyal Ashkenazi 1 , Yulia Kovalev 1 , Oranit Cohen Ezra 1,2 , Ella Weitzman 3 , Tarek Saadi 3 , Matthias Carlebach 4 , Rawi Hazzan 5 , Rifaat Safadi 6 , Tova Goldberg 6 , Ran Oren 6 , Yafa Ashur 7 , Michal Carmiel 8 , Yona Kitayi 9 , Ruth Hadari 9 , Seif Abu-Mouch 10 , Rafael Bruk Bruk 11 , Yoram Menachem 11 , Helena Kathcman 11 , Oren Shibolet 11 , Orly Sneh 12 , Haim Shirin 13 , Ran Tur-Kaspa 14 , Marius Broun 14 , Michal Cohen Naftaly 14 , Amir Shlomai 14 1 Liver Unit, Carmel Medical Center, Technion Faculty of Medicine, Israel 2 Center of Liver Diseases, Sheba Medical Center, Israel 3 Liver Unit, Rambam Medical Center, Israel 4 Liver Unit, Bnai Zion Medical Center, Israel 5 Liver Clinic, Ha'emek Medical Center, Israel 6 Liver Unit, Hadassah Medical Center, Israel 7 Liver Clinic, Southern District, CHS, Israel 8 Liver Clinic, Western Galilee Medical Center, Israel 9 Liver Clinic, Meir Medical Center, Israel 10 Liver Unit, Hillel Yaffe Medical Center, Israel 11 Liver Unit, Tel Aviv Medical Center, Israel 12 Liver Clinic, Talpiot Clinic, CHS, Israel 13 Department of Gastroenterology, Assaf Harofeh Medical Center, Israel 14 Liver Institute, Rabin Medical Center, Israel 

 

12:18-12:26  Vertical HBV transmission in North West Galilee

Jamalat Jaas 1 , Rifaat Safadi 2 , Shihab Shihab 1 1 Acre Health Bureau, Israeli Ministry of Health, Akco District, Israel 2 Liver and Gastroenterology Units, Hadassah-Hebrew University Hospital, Israel 

 

12:26-12:34  Hepatitis B virus infection after the implementation of the vaccine program in Israel

Eli Zuckerman 1 , Hedy S. Rennert 2 , Gad Rennert 2 1 Liver Unit, Carmel Medical Center, Technion Faculty of Medicine, Israel 2 community Medicine and department of Epidemiology, Carmel Medical Center, Israel 

12:34-12:42  Hepatitis E Virus in Israeli HIV Infected Patients  

Rasha Daniel 1,2,4 , Shira Zelber-Sagi 2 , Margalit Lorber 3 , Mira Barak 4 , Orly Azulay 1 , Eli Zuckerman 1 1 Liver Unit, Carmel Medical Center, Israel 2 Faculty of Public Health, Haifa University, Israel 3 Autoimmune, HIV/AIDS Disease Unit, RAMBAM Medical Center, Israel 4 Nesher Central Laboratories, Haifa and Western Galilee District, CHS, Israel 

 

12:42-12:50 Automated Low Flow Pump System (AlFAPUMPÓ) For the Treatment of Refractory Ascites- Initial Israeli Experience

Michal Cohen 1,3, Asaf Issachar 1,3,4, David Arnovitz 2,3, Orly Sneh- Arviv 1,3, Yaakov Maor 6, Yona Kitai 3,7, Amir Shlomai 1,3,4, Ran Tur Kaspa 1,5, Marius Braun 1,3

1 Liver Unit, Beilinson Hospital, Israel 

2 General Surgery Department, Beilinson Hospital, Israel 

3 Sackler Faculty of Medicine, Tel Aviv University, Israel 

4 Internal Medicine Department D, Beilinson Hospital, Israel 

5 Faculty of Medicine, Bar Ilan University , Israel 

6. Head, Liver Unit, Kaplan Medical Center, Israel

7. Head, Internal Medicine Department C & Unit Liver Diseases, Meir Hospital, Israel


12:50-13:00  Mr. Hulio Burman

13:00-13:30 Business Meeting


 13:30-14:30   Lunch   Hotel's Restaurant