Sunday, 30th March
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Welcome
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09:00-09:10
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Session 1, Chairs:
Julien Vermot, IGBMC, France
Nathan Lawson, University of Massachusetts Medical School, Worcester, MA, USA
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09:10-10:50
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Yaron Shav Tal, Bar-Ilan University, Israel
Quantifying mRNA transcription in single living cells
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09:10
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Hernan Lopez-Schier, SBO, Helmholtz Zentrum München, Munich, Germany
Establishment and regeneration of epithelial mirror symmetry
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09:30
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Nadine Peyrieras, INAF, CNRS, Gif sur Yvette, France
Reconstructing multi scale in vivo imaging data by multilevel dynamics
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09:50
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Periklis Pantazis, D-BSSE, ETH Zurich, Basel, Switzerland
PhOTO Zebrafish: A Transgenic Resource for In Vivo Lineage Tracing during Development and Regeneration
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10:10
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Julien Vermot, IGBMC, France
Imaging cilia biomechanics in 3D using modelling and correlative microscopy
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10:30
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Coffee Break
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10:50-11:30
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Session 2, Chairs:
Lior Appelbaum, Bar Ilan University, Israel
Koichi Kawakami, National Institute of Genetics, Mishima, Shizuoka, Japan
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11:30-13:15
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Adi Mizrahi, The Hebrew University of Jerusalem, Israel
New neurons in adult brains - insights from in vivo imaging
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11:30
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Didier Stainier, MPI, Germany
High Resolution Imaging of Cardiomyocyte Behavior Reveals Two Distinct Steps in Ventricular Trabeculation
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11:50
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Erez Raz, Münster University, Münster, Germany
Motility and Directed migration of Primordial Germ Cells in zebrafish
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12:10
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Carl-Philipp Heisenberg, IST Austria, Klosterneuburg, Austria
Cell and tissue mechanics in zebrafish gastrulation
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12:30
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Darren Gilmour, EMBL, Heidelberg, Germany
Quantitative cell polarity imaging defines leader to follower transitions during collective migration and the key role of microtubule dependent adherens junction formation
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12:50
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Lunch
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13:15-14:30
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Shuttles from Weizmann Institute to Ein Gedi for the EZPM participants only
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14:30
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Registration
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16:00
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Dinner
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18:30
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Welcome and keynote lecture by Uri Alon, Weizmann Institute, Israel
Chair:
Karina Yaniv, Weizmann Institute of Science, Israel
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20:00
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Cocktail Reception
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21:00
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Monday, March 31, 2014
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Breakfast
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07:30-09:00
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Development and Organogenesis I
Chairs:
Brant Weinstein, NICHD, NIH, Bethesda, MD, USA
Wiebke Herzog, University of Muenster, Muenster, Germany
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09:00-10:45
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Nadia Mercader, Centro Nacional de Investigaciones Cardiovasculares CNIC, Spain
Epicardium morphogenesis is driven by heartbeat-driven pericardiac fluid forces
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09:00
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Karina Yaniv, Weizmann Institute of Science, Israel
A pool of unspecified endothelial progenitors within the floor of the PCV gives rise to the lymphatic system during embryonic development
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09:15
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Wiebke Herzog, University of Muenster, Germany, Max Planck Institute for Molecular Biomedicine, Germany
Canonical Wnt-signaling regulates angioblast versus erythrocyte specification
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09:30
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Christian Mosimann, University of Zürich, Switzerland
Transcriptional control of early lateral mesoderm cell fates
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09:45
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Martin Gering, University of Nottingham, UK
The gene-trap line qmc551 suggests an important role for the Gfi1 transcription factor during haematopoietic stem cell formation in the vertebrate embryo
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10:00
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Brant Weinstein, NICHD, NIH, USA
Lost in translation: Phosphoinositide recycling and angiogenesis
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10:15
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Virginie Lecaudey, University of Freiburg, Germany
Amotl2a interacts with the Hippo pathway to control organ size in the zebrafish lateral line
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10:30
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Coffee Break
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10:45-11:15
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Stems Cells and Regeneration
Chairs:
Gilbert Weidinger, Ulm University, Ulm, Germany
Nadia Mercader, CNIC, Madrid, Spain
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11:15-13:00
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Tatjana Piotrowski, Stowers Institute for Medical Research, USA
Notch signaling maintains stem cell compartments by controlling cell division patterns and its downregulation is crucial for hair cell regeneration
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11:15
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Laure Bally-Cuif, Laboratory of Neurobiology and Development, Institute of Neurobiology A. Fessard, France
Controlling neural stem cell formation and activation in the adult zebrafish telencephalon
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11:30
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Antonio Jacinto, NOVA Medical School, Portugal
Regulation of tissue growth during zebrafish caudal fin regeneration
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11:45
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Alon Kahana, University of Michigan, USA
Muscle de-differentiation and motoneuron remodeling in a zebrafish model of muscle injury
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12:00
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Gilbert Weidinger, Ulm University, Germany
Wnt/b-catenin signaling defines organizing centers that orchestrate growth and differentiation of the regenerating zebrafish caudal fin
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12:15
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Stefania Nicoli, Yale Cardiovascular Research Center, USA
DICER destabilization is required to determine miR-9 threshold during neurogenesis
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12:30
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David Traver, UCSD, USA
FGF Signaling is Required at Multiple Stages for Hematopoietic Stem Cell Emergence
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12:45
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Lunch
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13:00-14:30
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Cell Biology and Cell Migration I
Chairs:
Carl-Philip Heisenberg, IST Austria, Klosterneuburg, Austria
Maximilian Furthauer, Insitut de Biologie Valrose, Nice, France
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14:30-16:15
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Florencia Cavodeassi, Centro de Biologia Molecular Severo Ochoa (CSIC/UAM), Spain
Dissecting the molecular mechanisms underlying early eye formation
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14:30
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Uwe Straehle, Karlsruhe Institute of Technology (KIT), Germany
Distinct cranial neural crest populations contribute to the development of the eye
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14:45
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Caren Norden, Max Planck Institute for Cell Biology and Genetics, Germany
Nuclear apical migration and apical mitosis occur independently of centrosome position in neuroepithelia ensuring the robustness of the process important for neural tissue maturation
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15:00
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Maximilian Fürthauer, Insitut de Biologie Valrose, France
Zebrafish ESCRT proteins contribute to the formation and function of ciliated organs
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15:15
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Alexander Schier, Harvard University, USA
Towards a quantitative understanding of nodal signaling
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15:30
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Arndt Siekmann, Max Planck Institute for Molecular Biomedicine, Germany
Live imaging of blood vessel formation reveals a central role of the chemokine receptor cxcr4a during artery formation
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15:45
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Coffee Break
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16:15-16:45
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Neuroscience I
Chairs:
Herwig Baier, Institute of Neurobiology, Martinsried, Germany
Filippo del Bene, Institut Curie, Paris, France
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16:45-19:00
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Herwig Baier, Max Planck Institute of Neurobiology, Germany
The visual projectome: Retinal ganglion cell diversity underlies computational complexity in the visual system
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16:45
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Lior Appelbaum, Bar Ilan University, Israel
Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation
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17:00
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Claire Wyart, Institut du Cerveau et de la Moelle Epiniere, France, Inserm U975, France, Universite Pierre et Marie Curie, France
Optical probing of circuits underlying sensory motor integration in the spinal cord
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17:15
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Corinne Houart, MRC Centre for Developmental Neurobiology, King's College London, UK
Temporal regulation of signalling centres in control of brain size and complexity
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17:30
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Stephan C.F. Neuhauss, University of Zurich, Switzerland
Cone Phototransduction Cascade Shutoff is Regulated by Multiple Recoverin Proteins and Influenced by the Circadian Clock
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17:45
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Thomas Dickmeis, Karlsruhe Institute of Technology, Germany
A transgenic zebrafish line for monitoring the core feedback loop of the circadian clock
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18:00
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Dinner
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19:00-20:00
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Poster Session (All posters)
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20:30-22:00
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Tuesday, April 1, 2014
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Buses Departure to Masada
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06:00
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Morning Coffee and Pastry
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06:15-06:30
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Sunrise Hike to Masada
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06:30-08:30
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Breakfast in Ein Gedi Hotel
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09:00-10:00
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Development and Organogenesis II
Chairs:
Didier Stainier, MPI, Germany
Elke Ober, University of Copenhagen, Denmark
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11:00-12:30
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Elke Ober, University of Copenhagen, Denmark, National Institute for Medical Research, UK
Liver progenitor specification - a crosstalk between Wnt and Bmp signalling
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11:00
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Mary Mullins, University of Pennsylvania, USA
Dynamics and Shaping of the BMP Signaling Gradient in DV axial Patterning
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11:15
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Stefan Schulte-Merker, KNAW & UMC Utrecht, The Netherlands
Divergence of lymphatic cell fate specification pathways between zebrafish and mice
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11:30
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Berta Alsina, Universitat Pompeu Fabra, Spain
Formation of the inner ear cavity in real-time: new mechanisms for lumen shaping
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11:45
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Patrick Mueller, Max Planck Institute for Developmental Biology, Germany
Identification of Nodal diffusion regulators
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12:00
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Francesco Argenton, Università degli Studi di Padova, Italy
Smad3 mediated TGFbeta signalling controls the progenitor/precursor switch during zebrafish CNS development
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12:15
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Lunch
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12:30-14:00
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Cancer and Disease Model I
Chairs:
Freek Van Eden, University of Sheffield, Sheffield, UK
Marina Mione, Institute of Technology, Germany
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14:00-15:30
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Jean-Pierre Levraud, Institut Pasteur, France
Spatial dynamics of viral infections and anti-viral immunity: lessons from imaging chikungunya virus-infected zebrafish
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14:00
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Ana Cvejic, University of Cambridge, UK
A loss of function screen of identified genome-wide association study loci reveals new genes controlling haematopoiesis
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14:15
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Dimitris Beis, Biomedical Research Foundation, Academy of Athens, Greece
Zebrafish myh6-/- adults survive with a single-chamber heart, presenting a cardiac hypertrophy disease model
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14:30
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Salim Seyfried, Hannover Medical School, Germany, Max Delbrück Center for Molecular Medicine, Germany
Exiting angiogenesis requires CCM proteins to attenuate proangiogenic Klf2activity
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14:45
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Yury Miller, University of California San Diego, USA
Transgenic zebrafish models of lipid metabolism
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15:00
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Bettina Schmid, German Center for Neurodegenerative Diseases, Germany, Cluster for Systems Neurology, Germany
Zebrafish models of Amyotrophic Lateral Sclerosis
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15:15
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Coffee Break
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15:30-16:00
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Neuroscience II
Chairs:
Corinne Houart, King's College London, UK
Steffen Scholpp, Institute of Toxicology and Genetics (ITG),Karlsruhe, Germany
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16:00-17:30
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Stephen Wilson, UCL, UK
Left-right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli
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16:00
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Reinhard W. Köster, TU Braunschweig, Germany
Non-invasive in vivo mapping of cerebellar Purkinje cell connectivity by trans-neuronal tracing, physiological analysis and optogenetic functional modulation
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16:15
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Gil Levkowitz, Weizmann Institute of Science, Israel
Assembly and functionality of oxytocin neuronal circuits
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16:30
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Filippo Del Bene, Institut Curie, France
Anterograde axonal transport involvement in synaptic function, branch pruning and arbor development
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16:45
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German Sumbre, Ecole Normale Superieure, France
Spontaneous neuronal activity patterns reveal circuit functional mechanisms that predict behavioural performance
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17:00
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Steffen Scholpp, Institute of Toxicology and Genetics (ITG), Germany
Filopodia based transport of Wnt during vertebrate tissue patterning
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17:15
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Coffee Break
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17:30-18:00
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Emerging Technologies
Chairs:
Stefan Schulte Merker, KNAW & UMC Utrecht, Utrecht, The Netherlands
Alex Schier, Harvard University, USA
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18:00-19:00
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Henry Krause, University of Toronto, Canada
Transgenic lines for the identification of nuclear receptor ligands, cofactors and pathways
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18:00
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Nathan Lawson, University of Massachusetts Medical School, USA
Reverse genetics in zebrafish: the good, the bad, and the ugly
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18:15
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Koichi Kawakami, National Institute of Genetics, Mishima, Shizuoka, Japan
Genetic dissection of the adult zebrafish brain by the Gal4-UAS method
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18:30
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Máté Varga, Eötvös Loránd University, Hungary
Molecular tattooing in live zebrafish: the use of photoinducible reagents to regulate molecular processes in space and time
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18:45
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Dinner
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19:30-20:30
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Poster Session (All posters)
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20:30-22:00
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Wednesday, April 2, 2014
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Breakfast
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07:30-09:00
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Behavior
Chairs:
Hitoshi Okamoto, RIKEN, Wako, Saitama, Japan
German Sumbre, Ecole Normale Superieure, Paris, France
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09:00-10:30
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Gonzalo de Polavieja, Instituto Cajal, CSIC, Spain
Group behavior in zebrafish
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09:00
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Marnie Halpern, Carnegie Institution for Science, USA
Development and Function of Habenular Neurons
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09:15
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Philippe Mourrain, Stanford University, USA, INSERM, France
DIAMOND: Shining light on vertebrate behavior
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09:30
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William HJ Norton, University of Leicester, UK
The genetic and neurological basis of zebrafish aggression
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09:45
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Yoav Gothilf, Tel Aviv University, Israel
Connecting genes to circadian locomotor activity
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10:00
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Hitoshi Okamoto, RIKEN, Japan
The ventral habenula in zebrafish assigns the negative prediction value to the conditioned stimulus in the active avoidance learning
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10:15
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Coffee Break
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10:30-11:00
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Cell Biology and Cell Migration II
Chairs:
Erez Raz, Münster University, Münster, Germany
Dimitris Beis, Biomedical Research Foundation, Academy of Athens, Greece
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11:00-12:45
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Heinz-Georg Belting, Biozentrum/Uni Basel, Switzerland
Shaping the stalk: VE-cadherin promotes dynamic cell shape changes during angiogenic sprouting by coupling the cortical actin network to endothelial cell interfaces
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11:00
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Steven A. Farber, Carnegie Istitution for Science, USA
A method to visualize apolipoproteins in live zebrafish:Liver-derived APOA-I localizes to an apical domain of intestinal enterocytes
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11:15
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Roland Dosch, Georg-August University Goettingen, Germany
Souffle/Spastizin Controls Secretory Vesicle Maturation during Oogenesis
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11:30
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David Whitmore, University College London, UK
Light responsive circadian clocks in teleosts and how they have changed following evolution in a cave environment
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11:45
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Masazumi Tada, University College London, UK
Live-imaging and genetic analyses of transformed cell extrusion from the zebrafish embryonic epithelium
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12:00
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Susana Lopes, NOVA University, Faculty of Medical Sciences, Portugal
Targets of Notch/Delta signaling in Kupffer’s vesicle ciliated epithelia
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12:15
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Lunch
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12:30-14:00
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EUFishBioMed Society Assembly
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13:00-14:00
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Cancer and Disease Models II
Chairs:
Uwe Strahle, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany
Liz Patton, University of Edinburgh, Edinburgh, UK
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14:15-16:00
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Marina Mione, Karlsruhe Institute of Technology, Germany
Notch pathway is activated by oncogenic ras in a zebrafish model of glioma and blocks neuronal differentiation
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14:15
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Liz Patton, University of Edinburgh, UK
A new BRAFV600E melanoma model reveals mitf is essential for cancer promotion versus regression in vivo
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14:30
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Ewa Snaar-Jagalska, Institute of Biology, The Netherlands
Novel treatment strategies for prostate, Ewing sarcoma and breast cancer facilitated by HT platforms for zebrafish xenografts
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14:45
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Jeroen den Hertog, Hubrecht Institute-KNAW and University Medical Center Utrecht, The Netherlands, Institute Biology Leiden, The Netherlands
PTEN has an essential role in the balance between proliferation and differentiation of blood cells
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15:00
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Manfred Schartl, University of Wuerzburg, Germany
Analysis of small non-coding RNAs in melanoma
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15:15
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Freek van Eeden, University of Sheffield, UK
Von Hippel Lindau-like genes in zebrafish and DNA repair
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15:30
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Desert Hiking + Dinner Party
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16:30-23:00
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Thursday, April 3, 2014
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Breakfast
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07:30-09:00
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Omics
Chairs:
Derek Stemple, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
Stefania Nicoli, Research Center, New Haven, CT, USA
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09:00-10:30
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Derek Stemple, Wellcome Trust Sanger Institute, UK
Transcript counting as a molecular phenotyping tool
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09:00
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Bernard Peers, University of Liège, Belgium
Transcriptome analysis by RNA-seq of the distinct pancreatic cell types
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09:15
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Ferenc Mueller, Barcelona, Spain
What can zebrafish tell us about how are genes get switched on
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09:30
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Thomas Becker, University of Sydney, Australia
Probing post embryonic and adult gene function through synthetic micro RNAs
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09:45
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Closing
Chair:
Yoav Gothilf, Tel Aviv University, Israel
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10:00
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Community Meeting
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10:20
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Tour to Jerusalem
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11:00
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Lunch on Tour
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13:00
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Tour Continue
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14:30
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End of Tour
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18:00
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Transfers to Airport and Tel Aviv Hotels
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18:00
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